They also have hypnotic, anticonvulsant and muscle-relaxing activities, but do not exhibit analgesic action or antipsychotic activity.The representatives of this group are: Nonbenzodiazepine “Z-drugs” sedative-hypnotics are drugs that differ in structure from benzodiazepines, but acts on a subset of the benzodiazepine receptor family known as BZ1." April 25, 2003 -- Timely research for the start of hay fever season: Despite their higher cost, the newer, so-called "second generation" of more expensive "nonsedating" prescription antihistamines may be no more effective at preventing fatigue and memory lapses than older over-the-counter formulas such as Benadryl.So concludes a new study published in the current issue of Journal of Allergy and Clinical Immunology in which researchers compared 18 previous trials investigating antihistamine-caused sedation levels in 1,500 people between ages 8 and 81.Additional administration of epinephrine, often in the form of an autoinjector (Epi-pen), is required by people with such hypersensitivities.H-antihistamines can be administered topically (through the skin, nose, or eyes) or systemically, based on the nature of the allergic condition.
"In some studies we reviewed, some people actually experienced more sedation with the newer, nonsedating formulas than with the older, sedating products.
Sedatives encompass a wide variety of drugs with different mechanisms of action that can induce depression of the central nervous system (CNS).
In the first part of the 20th century, the pharmacotherapy of anxiety and insomnia relied on barbiturates, which were replaced with benzodiazepines as drugs of choice in the second part of the previous century.
The representatives of this group are: Benzodiazepines are the most widely used group of sedative drugs.
Due to their safety and improved effectiveness, they have largely replaced barbiturates as drugs of choice in the treatment of anxiety.